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Institute for Advanced Academic Research / Faculty of Medicine / Research Institute of Disaster Medicine, Chiba University
ProfessorThe genome is the blueprint of life. The “which part” of the genome is read differs in each cell, and the addition or deletion of the methyl group CH3- (just four atoms) plays an important role in reading the genome. This mechanism is known as epigenetic modification, and the development of next-generation sequencing technology has greatly contributed to this research field. Epigenetic modifications by methyl groups can be classified into two types: (1) methylation of histones and (2) methylation of DNA cytosines. Our previous research showed that histone methylations regulated by the Polycomb and Trithorax group proteins are essential for immune responses, particularly those mediated by T cells. In addition, our recent international collaborative study revealed that TET enzymes, which convert methyl-cytosine into hydroxymethyl-cytosine, inhibit inflammation and tumor development in mice and humans. Currently, our study focuses on the relationship between age-related epigenetic abnormalities and immune diseases, which has received much attention in recent years. The final goal of my research is to solve the mysteries of life and ultimately control diseases by concentrating our wisdom on physics, chemistry, and mathematics.
Recent Topics of Interests:
Cancer immunotherapy by epigenetic manipulation, Immuno-aging caused by epigenetic abnormalities, Integrative single-cell multi-omics analyses
Motto in Research or in Life:
The motto in research: Let’s enjoy science!
The motto in life: “If you put your mind to it, you could accomplish anything.” This quote is cited from Back to the Future, Universal Pictures, 1985.
Hobby / Holiday:
Reading books, Watching baseball games, Insect hunting
Faculty of Law, Politics and Economics / Research Institute of Disaster Medicine, Chiba University
ProfessorI specialize in European political history and comparative politics, with a particular focus on the Netherlands. My research interests encompass various topics, including ongoing welfare and labor reforms in European countries, the impact of populism on established political parties and parliamentary politics, developments concerning minority groups such as Jews, and the intricate relationship between monarchies and democracy.
Recent Topics of Interest: Urban regeneration and the role of “neighborhood” are central themes that directly impact shaping the community’s approach to disaster prevention.
Motto in Research or in Life: Once-in-lifetime-“word” (as a researcher dedicated to the study of the power of conversation)
Hobby / Holiday: Travelling and “Exploring towns”
Faculty of Medicine / Research Institute of Disaster Medicine, Chiba University
ProfessorI graduated from Chiba University School of Medicine in 1984 and subsequently joined the Department of Neuropsychiatry at Chiba University. In 1986, I embarked on a research position at the National Center for Psychiatry and Neurology, followed by a visiting researcher role at the National Institutes of Health (NIH) in the United States in 1988. Upon my return to Japan, I held several key positions, including Director of the Drug Dependence Laboratory at the Institute of Mental Health, National Center for Neurology and Psychiatry, and Associate Professor of Neuropsychiatry at Hamamatsu University School of Medicine. Eventually, in 2000, I joined Chiba University.
My areas of expertise include psychopharmacology, cognitive-behavioral therapy, establishing community mental health care systems, disaster and emergency psychiatric medicine, sports psychiatry, and forensic psychiatry. In recent years, my research has been primarily focused on advancing our understanding of the pathology of schizophrenia, with a particular emphasis on treatment-resistant schizophrenia. I am dedicated to developing effective treatment methods for this condition.''
Faculty of Nursing / Research Institute of Disaster Medicine, Chiba University
ProfessorI am conducting research on the practical activities of public health nurses in the administrative field and focusing on the clarification of preventive techniques and capacity development in public health nursing. In particular, due to the comprehensive utilization of public health nurses' abilities during disasters, we are continuously conducting investigations and research on their activities during such times. We are working on the development of evaluation indicators, practice guides, and training programs for activities during disasters, which are being used in various locations.
Recent Topics of Interest: System establishment for activities during health crises.
Motto in Research or in Life: Every experience is valuable.
Hobby / Holiday: Nature exploration, Buddhist statues appreciation.
Medical Mycology Research Center / Research Institute of Disaster Medicine, Chiba University
ProfessorInfectious diseases caused by RNA viruses, such as COVID-19 and Influenza, are significant threats to our daily lives. In order to overcome them, I am working on analyzing the physiological significance and molecular mechanism of anti-viral signaling induced by host RNA sensors in our innate immune system and trying to gain valuable insights that can contribute to developing therapeutic strategies for emerging infectious diseases.
Recent Topics of Interest: Interaction between Anti-viral and Stress Responses
Faculty of Horticulture / Research Institute of Disaster Medicine, Chiba University
ProfessorI am researching the role of landscape in enhancing the interaction between human activities and the natural environment. Specifically, I am exploring how landscape can shape this relationship in urban spaces, preserve green spaces in development projects, and contribute to land-use strategies that mitigate the impact of natural disasters. Ultimately, I aim to improve the connection between human activities and the natural environment through innovative landscape initiative approach aspects.
Recent Topics of Interest:
I am interested in green space policy and land use management, river basin flood control, resident consensus buildings, and landscape governance. Specifically, I am examining new disaster prevention and post-disaster planning approach in response to the high incidence of disasters associated with climate change in recent years. Additionally, I am also exploring the issue of gender in spatial planning.
Motto in Research or in Life: There is nothing worthless in our lives.
Hobby / Holiday: Jazz piano (as I haven’t had much time to practice, it’s a “half wish.” I will work hard from now on!)