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Graduate School of Medicine, Chiba University / Health and Disease Omics Center
Professor / DirectorCells accumulate abnormalities in their genomic and epigenomic information, which can lead to diseases like cancer. The epigenome, which involves modifications to the genome, changes due to environmental factors and stress such as aging, infection, and inflammation in somewhat defined manners, resulting in cell fate alteration. Exploring and harnessing the accumulated epigenomic aberrations is a crucial step in elucidating cancer and developing novel cancer treatments.
Recent Topics of Interests:
Cancer risk diagnosis, Integrated omics analysis
Motto in Research or in Life: Insatiable inquiry and challenge
Institute for Advanced Academic Research / Graduate School of Medicine, Chiba University
ProfessorMy research focuses on developing and applying minimally invasive, everyday measurement methods, such as wearable devices and saliva-based testing, alongside advancing AI and mathematical analysis technologies for the early detection and prediction of diseases.
I mainly target infectious diseases, inflammatory diseases, and lifestyle-related illnesses, which often arise and progress due to multifactorial causes. Through the integrating large-scale clinical data, specimen collection, and cutting-edge AI and data science technologies, I purse researching on disease stratification as well as disease onset and prognosis prediction.
Recent Topics of Interest:
・ Health and disease assessment using time-series data (moving beyond single-point test values to gain deeper insights)
・ Dynamic causal inference (potentially valuable for selecting treatments tailored to evolving pathological conditions, transitioning from prediction to intervention).
・ Mathematical optimization (to explore experimental and treatment conditions that have traditionally been determined empirically.)
Motto in Research or in Life:
・ Strategically placing stones towards a big goal.
・ Considering myself as one of the pawns to maximize research outcomes.
・ Students and research fellows are also equal collaborators.
・ The purpose of research is not to gain achievements or fame but to contribute to society by uncovering and implementing the truth.
Hobby / Holiday:
I have enjoyed playing the drums for 20years. I also value spending with my family solving puzzles, including escape games and other challenges.
Graduate School of Medicine, Chiba University
Assistant ProfessorI specialize in the diagnosis and treatment of ankle and foot-related conditions, as well as conducting research in this field.
During my Ph.D. studies, I conducted research on the use of platelet-rich plasma (PRP), a hot topic in sports orthopedics and regenerative medicine, to promote tendon repair following Achilles tendon rupture.
Recent Topics of Interest: Utilization of ultrasound (echo) in foot-related issues.
Motto in Research or in Life: Let’s have fun together.
Hobby / Holiday: Tennis, Family Outing
Graduate School of Medicine, Chiba University
ProfessorMy research focuses on scientifically investigating the underlying causes of women's health issues, particularly those unique to women, such as menstruation, pregnancy, childbirth, and menopause. I aim to establish innovative preventive and treatment methods while building evidence to create systems and environments where women can access accurate information and make informed, autonomous decisions about their health. This is especially important for addressing matters related to sexuality and reproductive health.
Recent Topics of Interest:
Basic Medical Science: Research utilizing comprehensive analytical approaches, including multi-omics data, to uncover the mechanisms of gynecological diseases such as endometriosis and to develop novel therapeutic strategies.
Social Medicine: Interdisciplinary research integrating behavioral psychology, neuroscience, and economics to promote behavioral change, with a particular focus on menstrual-related diseases and their impact on working women’s quality of life and labor productivity.
Motto in Research or in Life: Grace under pressure
Hobby / Holiday:
I'd like to say "Work is my hobby", but these days such a response might not be appropriate. Lately, I've been making a conscious effort to do things that will benefit me in the next five years—taking care of my health, learning about things other than medicine, or giving cooking a try for the first time (laugh!).
Institute for Advanced Academic Research / Graduate School of Medicine, Chiba University
Associate ProfessorThe “intestinal mucosa” serves not only as a site for digestion and absorption, but also plays a crucial role in biological regulation, including the immune system. Through research on intestinal mucosal immunity, we are making efforts to establish treatments for diseases such as fibrotic and allergic diseases (e.g., inflammatory bowel disease and food allergy), which can result in multi-organ failure. Furthermore, in recent years, intestinal bacteria capable of crossing the intestinal barrier and infecting and translocating extra-intestinal organs have been regarded as the potential “causes of various diseases.” Therefore, we are conducting research aimed to identify and control pathogenic commensal bacteria. Our ongoing immunological research is progressing diligently and steadily.
Recent Topics of Interest: Organ axis, Pathogenic commensal bacteria, Peripheral immune education, Inflammatory bowel disease
Motto in Research or in Life: When the going gets tough, the tough get going.
Fixed ideas are evil; prejudices are sin.
Hobby / Holiday: Martial arts, Movies, Photography
Graduate School of Medicine, Chiba University
Professor / DeanI am conducting fundamental medical research on the regulation of sugar and energy metabolism. My primary research interests lie in investigating inter-organ networks and intracellular signal pathways. Specifically, I am exploring innovative treatments for conditions such as diabetes, obesity, and non-alcoholic fatty liver disease.
Additionally, I actively contribute to promoting research in the field of disaster medicine, with the ultimate goal of fostering a resilient society that can effectively protect people's health during and after emergencies and disasters.
Motto in Research or in Life:
Necessity is the mother of invention. Where there's a will, there's a way. Nothing ventured, nothing gained.
Graduate School of Medicine, Chiba University
ProfessorI am engaged in research to develop innovative cancer treatments using immune cells, specifically exploring the intricate relationship between cancer and the immune system as a mechanism of its effectiveness. Moreover, I am vigorously conducting efforts, including clinical trials, to swiftly provide treatment to patients in need.
Recent Topics of Interests: Tumor immunology research
Motto in Research or in Life:
There is no need for "For now" or "Sort of."
If I'm going to work on it, I'll give it my all.
Hobby / Holiday:
Reading, Practicing Volleyball for a Senior Volleyball Tournament
Institute for Advanced Academic Research / Graduate School of Medicine, Chiba University
LecturerThe molecular mechanism of carcinogenesis mediated by extrachromosomal DNA (ecDNA) remain largely unknown, despite increasing interest in this area in recent years. Previous studies have identified the presence of ecDNA in virus-associated cancers, where segments of the human and viral genomes are fused to form human-viral hybrid ecDNA (hybrid ecDNA). These studies have also suggested that hybrid ecDNA may play a critical role in tumorigenesis. My current research aims to elucidate the oncogenic functions of hybrid ecDNA by performing multi-omics analyses of clinical specimens and integrating clinical imaging, nutritional information, and other datasets. Through this work, I seek to develop novel therapeutic strategies to overcome virus-associated cancers.
Recent Topics of Interest:
extrachromosomal DNA (ecDNA), Spatial transcriptome analysis, AI
Motto in Research or in Life:
Always strive to stay one step ahead of the status quo
Hobby / Holiday:
Enjoy playing baseball and soccer, appreciating art, and discovering natural wine
Graduate School of Medicine, Chiba University
ProfessorMy goal is to elucidate the cellular and molecular mechanisms underlying diseases caused by immune system overreactions, such as allergic conditions including bronchial asthma and autoimmune diseases like rheumatoid arthritis. I aim to develop treatments based on these findings.
I am particularly interested in understanding the mechanisms that control T cell activation, which plays a central role in immune system dysregulation, and exploring the epigenetic regulation of immune memory.
Recent Topics of Interest:
(1) Understanding the cellular and molecular mechanisms underlying the development of allergic diseases, including asthma
(2) Investigating the cellular and molecular mechanisms involved in the development of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus
(3) Advancing treatments for allergies and autoimmune diseases through immune memory resetting strategies
Motto in Research or in Life:
Research motto
(1) I prioritize ‘intriguing’: I aim for research that is not only ‘intriguing’ medically but also biologically.
(2) I cherish the unexpected: I consider our hypotheses to be as small as grains of sand in the 4.6 billion years of Earth's history.
Motto in life
(1) I avoid turning down work whenever possible, but as a result, I am finding it increasingly difficult to do what I truly want.
(2) I try not to say “I have no choice" as much as possible; however, as a consequence, there’s a buildup of situations where it just can’t be helped.
(3) I strive not to make enemies, or at least that's my intention.
Hobby / Holiday:
Watching wombat videos, Traveling, especially visiting shrines and temples, Jogging during a trip, Visiting art galleries and museums
