Researchers

Graduate School of Medicine, Chiba University

Takayuki HOSHII

Associate ProfessorAlthough childhood cancers often involve little DNA damage, certain factors are known to drive tumor development. One such factor is "abnormal transcriptional regulation," which is increasingly believed to be linked to "epigenetic abnormality." Focusing on childhood leukemia models, I aim to develop novel drug targets through functional analysis of epigenetic factors that control cell proliferation.

Recent Topics of Interests:
The initiation of transcription can be compared to a track race, "Ready," "Set," and "Go." My research revealed that the disease-related proteins I study are involved in the "Set" phase, forming a complex and dynamic interaction network. I am currently working to functionally validate this network and explore ways to therapeutically intervene.
Motto in Research or in Life:
Keep making hypotheses, keep discarding hypotheses, and value the results.
Hobby / Holiday:
Running and caring for my aquarium